What is Cholesterol?

Cholesterol is a sterol (a combination steroid and alcohol). Cholesterol is a lipid found in the cell membranes of all tissues, and it is transported in the blood plasma of all animals. Because cholesterol is synthesized by all eukaryotes, trace amounts of cholesterol are also found in membranes of plants and fungi.The name originates from the Greek chole- (bile) and stereos (solid), and the chemical suffix -ol for an alcohol, as researchers first identified cholesterol in solid form in gallstones by Francois Poulletier de la Salle in 1769. However, it is only in 1815 that chemist Eugene Chevreul named the compound "cholesterine".[2]Most of the cholesterol is synthesized by the body and some has dietary origin. Cholesterol is more abundant in tissues which either synthesize more or have more abundant densely-packed membranes, for example, the liver, spinal cord and brain. It plays a central role in many biochemical processes, such as the composition of cell membranes and the synthesis of steroid hormones. Cholesterol is insoluble in blood, but is transported in the circulatory system bound to one of the varieties of lipoprotein, spherical particles which have an exterior composed mainly of water-soluble proteins. The main types, low-density lipoprotein (LDL) and high-density lipoprotein (HDL) carry cholesterol from and to the liver.According to the lipid hypothesis, abnormally high cholesterol levels (hypercholesterolemia) and abnormal proportions of LDL and HDL are associated with cardiovascular disease by promoting atheroma development in arteries (atherosclerosis). This disease process leads to myocardial infarction (heart attack), stroke and peripheral vascular disease. As high LDL contributes to this process, it is termed "bad cholesterol", while high levels of HDL ("good cholesterol") offer a degree of protection. The balance can be redressed with exercise, a healthy diet, and sometimes medication.

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JSTOR: Alcohol Consumption and Blood Pressure. An Italian Study
Alcohol and blood pressure in Italy RESULTS Systolic arterial pressure . Independently of the pathogenetic mechanism involved, alcohol appears to be a

Annals of Epidemiology : Gamma-glutamyltransferase, Alcohol, and
Author Keywords: Alcohol Consumption; Blood Pressure; Gamma-Glutamyltransferase; .. reflecting on GGT, as a possible mechanism of the relationship.

Alcohol and its relationship to blood pressure
information on the effects of alcohol on blood pressure . from a nonendothelium-based mechanism. Increasing blood pressure. Epidemiology (see Table 2)

ALCOHOL-INDUCED MACROCYTOSIS AND BLOOD PRESSURE
The mechanism through which alcohol in-. duces elevated blood pressure values is not. exactly known. Alcohol withdrawal is one

Alcohol and hypertension | Alcohol Health & Research World | Find
Experimental studies on animals have attempted to elucidate the mechanism by which alcohol affects blood pressure. In one study, male rats given 20-percent

IngentaConnect Effects of Alcohol Moderation on Blood Pressure and
It is known that moderation of alcohol intake reduces blood pressure, although the exact mechanism has not yet been established. To clarify the hypotensive

NEJM -- Alcohol and Blood Pressure -- A Drink a Day . . .
The article by Randin et al.1 addresses the potential mechanism of the acute pressor . Effects of alcohol intake on blood pressure and sympathetic nerve

Alcohol and blood pressure: a social comparison in Zimbabwe
Epidemiological evidence suggests that alcohol consumption is associated with increased blood pressure. However, a convincing physiological mechanism is

SHORT COMMUNICATION URINARY STEROID PROFILES AND ALCOHOL-RELATED
subsequent increase in blood pressure. The concept of. alcohol inducing hypertension by . has tested the hypothesis that one potential mechanism

PRESSOR EFFECT OF MODERATE ALCOHOL CONSUMPTION IN MAN: A PROPOSED
blood pressure and heart rate which occurred before the blood alcohol reached its . a slow pressor mechanism may not necessarily need large increases in

Alcohol and blood pressure mechanism. Dr. Cristine Cruthirds
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