What is Cholesterol?

Cholesterol is a sterol (a combination steroid and alcohol). Cholesterol is a lipid found in the cell membranes of all tissues, and it is transported in the blood plasma of all animals. Because cholesterol is synthesized by all eukaryotes, trace amounts of cholesterol are also found in membranes of plants and fungi.The name originates from the Greek chole- (bile) and stereos (solid), and the chemical suffix -ol for an alcohol, as researchers first identified cholesterol in solid form in gallstones by Francois Poulletier de la Salle in 1769. However, it is only in 1815 that chemist Eugene Chevreul named the compound "cholesterine".[2]Most of the cholesterol is synthesized by the body and some has dietary origin. Cholesterol is more abundant in tissues which either synthesize more or have more abundant densely-packed membranes, for example, the liver, spinal cord and brain. It plays a central role in many biochemical processes, such as the composition of cell membranes and the synthesis of steroid hormones. Cholesterol is insoluble in blood, but is transported in the circulatory system bound to one of the varieties of lipoprotein, spherical particles which have an exterior composed mainly of water-soluble proteins. The main types, low-density lipoprotein (LDL) and high-density lipoprotein (HDL) carry cholesterol from and to the liver.According to the lipid hypothesis, abnormally high cholesterol levels (hypercholesterolemia) and abnormal proportions of LDL and HDL are associated with cardiovascular disease by promoting atheroma development in arteries (atherosclerosis). This disease process leads to myocardial infarction (heart attack), stroke and peripheral vascular disease. As high LDL contributes to this process, it is termed "bad cholesterol", while high levels of HDL ("good cholesterol") offer a degree of protection. The balance can be redressed with exercise, a healthy diet, and sometimes medication.

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Two Classes of Blood Pressure Drugs Equally Effective - DukeHealth.org
A Not-So-Secret Way to Lower Your Blood Pressure in Two Weeks (ARBs) equally effective in controlling simple, uncomplicated high blood pressure.

Angiotensin II receptor blockers (ARBs) for high blood pressure -
Angiotensin II receptor blockers (ARBs) may be used alone or combined with other medicationâ”often a diureticâ”to treat high blood pressure.

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Also, whilst much research has identified the benefit of ACE, there is less evidence about ARBs. However, concerning blood pressure and diabetes,

AHRQ Effective Health Care Program - Reports
Comparing Two Kinds of Blood Pressure Pills: ACEIs and ARBs Both ACEIs and ARBs relax blood vessels, and that lowers blood pressure.

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This is converted by an enzyme to angiotensin II - the substance that constricts blood vessels and raises blood pressure. ACEIs and ARBs are designed to

High Blood Pressure and Kidney Disease
Many people need medicine to control high blood pressure. Two groups of medications called ACE (angiotensin-converting enzyme) inhibitors and ARBs

Angiotensin Receptor Blockers for High Blood Pressure Treatment
While more expensive than some of the older blood pressure medicines, ARBs have been shown to be very effective and may offer some benefits that other drugs

BMJ BestTreatments :: Conditions :: High blood pressure :: ARBs
If you have high blood pressure, taking an angiotensin II receptor blocker (or ARB for short) can lower your blood pressure and keep it down.

ARB Drug Controls Blood Pressure and Protects Kidneys - Diabetes
Irbesartan (Avapro), an angiotensin II receptor blocker (ARB), reduces 24-hour systolic and diastolic blood pressure as well as albumin excretion rate (AER)

ARB definition - Medical Dictionary definitions of popular medical
Angiotensin II Receptor Blockers (ARB) - Explains Angiotensin II Receptor Blockers (ARB), which are drugs used for controlling high blood pressure,

Medical News: ASH: ARB Plus Thiazide Slashes Blood Pressure But
NEW YORK, May 21 â” Diovan HCT (valsartan + hydrochlorothiazide) significantly reduced blood pressure compared with Diovan monotherapy, but at the cost of a

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For instance, the blood pressure goal for most people with diabetes is a an ARB, a beta blocker or a calcium channel blocker to adequately lower their

Angiotensin II Receptor Blockers (ARB'S) - High Blood Pressure
See how ARBs fight high blood pressure. Are ARBs (Angiotensin II Receptor Blockers) a part of the Program? Diovan is an ARB and Diovan HCT is a combination

Medications for hypertension and renal protection
As with the ACEI's, ARB's are first line blood pressure medications used in the context of chronic kidney disease. They will often be used when a patient

Angiotensin II Receptor Blockers (ARB) - drug class, medical uses
This narrowing increases the pressure within the vessels and can cause high blood pressure (hypertension). Angiotensin receptor blockers (ARBs) are

Angiotensin II receptor blockers (ARBs) - Yahoo! Health
Also, in people with type 2 diabetes and high blood pressure, ARBs are recommended in combination with ACE inhibitors as first-line treatment. 1

Angiotensin II receptor blockers (ARBs) for high blood pressure
These medications block the action of a hormone that causes blood vessels to narrow. As a result, blood vessels may relax and open up.

ARBS, ACE Inhibitors - High Blood Pressure (Hypertension) and
The effect is to widen the arteries, which lowers the blood pressure. For more about and examples of ARB drugs read MedicineNet.com's ARB medications


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