What is Cholesterol?Cholesterol is a sterol (a combination steroid and alcohol). Cholesterol is a lipid found in the cell membranes of all tissues, and it is transported in the blood plasma of all animals. Because cholesterol is synthesized by all eukaryotes, trace amounts of cholesterol are also found in membranes of plants and fungi.The name originates from the Greek chole- (bile) and stereos (solid), and the chemical suffix -ol for an alcohol, as researchers first identified cholesterol in solid form in gallstones by Francois Poulletier de la Salle in 1769. However, it is only in 1815 that chemist Eugene Chevreul named the compound "cholesterine".[2]Most of the cholesterol is synthesized by the body and some has dietary origin. Cholesterol is more abundant in tissues which either synthesize more or have more abundant densely-packed membranes, for example, the liver, spinal cord and brain. It plays a central role in many biochemical processes, such as the composition of cell membranes and the synthesis of steroid hormones. Cholesterol is insoluble in blood, but is transported in the circulatory system bound to one of the varieties of lipoprotein, spherical particles which have an exterior composed mainly of water-soluble proteins. The main types, low-density lipoprotein (LDL) and high-density lipoprotein (HDL) carry cholesterol from and to the liver.According to the lipid hypothesis, abnormally high cholesterol levels (hypercholesterolemia) and abnormal proportions of LDL and HDL are associated with cardiovascular disease by promoting atheroma development in arteries (atherosclerosis). This disease process leads to myocardial infarction (heart attack), stroke and peripheral vascular disease. As high LDL contributes to this process, it is termed "bad cholesterol", while high levels of HDL ("good cholesterol") offer a degree of protection. The balance can be redressed with exercise, a healthy diet, and sometimes medication. |
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Comparison of factors affecting daily variation of blood pressure These results suggest that the extent of blood pressure variation in daily life may depend upon cognitive processes which are influenced by the cultural Seasonal Variations in Blood Pressure It is important to take seasonal variations in blood pressure into as early as 1930,5 described the daily and monthly rhythms in blood pressure of men PENN Medicine News: First Molecular Evidence of Bodyâ™s Internal âœThis study provides evidence that integrates both explanations for the variation in blood pressure with clock time and, by inference, the daily variation Blood pressure measurement The information is recorded on a chip in the device and allows the doctor to get a detailed picture of blood pressure variation in a normal environment. High Blood Pressure: Heart and Blood Vessel Disorders: Merck Blood pressure also varies with the time of day: It is highest in the morning and lowest at night during sleep. These variations are normal. Circadian Blood Pressure Variation in Hypertensive Patients With The influence of behavioral factors on the daily variation of blood pressure. Am J Hypertens. 1993;6:170Sâ“173S.Medline Order article via Infotrieve Analysis of the daily variation in blood pressure and Analysis of the daily variation in blood pressure and pharmacokinetics after single or repeated administration of clentiazem to patients with essential Blood Pressure Variations and Correct Measurement - Heart Disease Blood in semen pressurePressure ulcer, daily medicine doses: atenonol(50mg), Its normal to have some cyclic variation in bloodAmylase - blood Ultradian rhythmic models of blood pressure variation in normal Ultradian rhythmic models of blood pressure variation in normal human daily life. BENTON LA, BERRY SJ, YATES FE. Chronobiologia 1990;17(2):95-116. Automated Ambulatory Blood Pressure Monitoring: Clinical Utility Daily Blood Pressure Variability. The literature describes a normal diurnal variation in blood pressure readings, an effect frequently chronicled by JAMA -- Abstract: Average daily blood pressure, not office blood Thus, the average daily blood pressure best predicts cardiac end-organ damage. Circadian Blood Pressure Variation in Hypertensive Patients With Primary |
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